Patched 1 antibody

Rabbit Polyclonal anti-Patched 1

Catalog Number: NB200-118	Price: $285.00

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Background:

Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas.

Alternate Names:

anti-PTCH antibody, anti-Human Patched Supressor Gene antibody

Host:

Rabbit

Research Areas:

Cancer Research, Growth and Development, Neuronal Markers

Immunogen:

A synthetic peptide made to residues 269-279 of the human and mouse PTCH protein.

Epitope:

Residues 269-279 [KKINYQVDSWE]

Species Reactivity:

This antibody reacts with human and mouse proteins. Other species have not been tested.
Other species have not been tested.

Homology:

Expected to cross react with rat and chicken due to 100% sequence identity.

Uses:

This antibody may be used for Western blot analysis where a band is seen at ~161 kDa.
Other applications have not been tested.

Dilutions:

Suggested working dilutions *
Western Blot 1:500 to 1:1,000
* Investigator should determine optimal working dilutions.

Packaging:

0.1 ml IgG purified Rabbit antisera.

Concentration:

1 mg/ml

Buffer:

PBS

Preservative:

0.02% sodium azide

Storage:

Store at 4C short term.  Aliquot and store at -20C long term.  Avoid freeze thaw cycles.

Limitations:

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 6 months from date of receipt.

General References:

1. Smyth et al. Hum. Mol. Genet. 8: 291-297, 1999.

Gene Id:

5727

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