Ocular Albinism 1 antibody

Rabbit Polyclonal anti-Ocular Albinism 1

Catalog Number: NLS2123	Price: $325.00

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Background:

Ocular albinism 1 (Nettleship-Falls; OA1) is an Orphan-U GPCR with an unknown ligand. Ocular albinism type 1 (OA1) is an inherited disorder characterized by severe reduction of visual acuity, photophobia, and retinal hypopigmentation. Ocular albinism type 1 protein is a conserved integral membrane protein with seven transmembrane domains. Misfolding of the OA1 protein has been suggested as a major pathogenic mechanism in OA1. OA1 protein expression has been documented in the eye and in epidermal melanocytes.

Alternate Names:

anti-ALBINISM OCULAR TYPE I antibody, anti-G protein coupled receptor 143 antibody, anti-GPR143 antibody, anti-MOA1 antibody, anti-NETTLESHIP FALLS TYPE OCULAR ALBINISM antibody, anti-OA1 antibody, anti-Ocular albinism type 1 protein antibody, anti-Ocular albinism type 1 protein homolog antibody, anti-Ocular albinism1 Nettleship-Falls type antibody

Host:

Rabbit

Research Areas:

GPCR (G Protein-Coupled Receptor), IHC Grade

Immunogen:

Synthetic peptide [KLH conjugated] made to the N-term extracellular

Epitope:

N-terminal extracellular domain of human

Species Reactivity:

Human. 45% identity and homology with mouse.
Other species have not been tested.

Uses:

Immunohistochemistry with formalin fixed paraffin embedded tissues. Optimal working dilutions should be determined by investigator.
Other applications have not been tested.

Dilutions:

Suggested working dilutions *
immunohistochemistry 16 ug/ml,
Immunohistochemistry-Paraffin 16 ug/ml
* Investigator should determine optimal working dilutions.

Packaging:

0.05 ml Affinity purified Rabbit antisera.

Concentration:

1 mg/ml

Buffer:

Phosphate buffered saline, PH 7.7

Preservative:

0.01% Sodium Azide

Storage:

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.

Limitations:

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 6 months from date of receipt.

Notes:

These products have been supplied by MBL International Corporation. Genbank accession number: NM_000273

Ocular Albinism 1 (Nettleship Falls; OA1) detection using NLS 2123 on human eye (retina).

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